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HBT-Fl-BnB

HBT-Fl-BnB is a fluorescent probe for the ratiometric detection of ONOO- in vitro and in vivo. HBT-Fl-BnB consists of an HBT core with Fl groups at the ortho and para positions responding to the zwitterionic excited-state intramolecular proton-transfer (zwitterionic ESIPT) process and a boronic acid pinacol ester with dual roles that block the zwitterionic ESIPT and recognize ONOO-[1].

Product Specifications

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/hbt-fl-bnb.html

Solubility

10 mM in DMSO

Smiles

CC(O1)(C)C(C)(C)OB1C(C=C2)=CC=C2OC3=C(C=C(C4=CC(C(C=CC=C5)=C5C6(CCCCCC)CCCCCC)=C6C=C4)C=C3C7=CC(C(C=CC=C8)=C8C9(CCCCCC)CCCCCC)=C9C=C7)C%10=NC%11=C(S%10)C=CC=C%11

Molecular Formula

C75H88BNO3S

Molecular Weight

1094.38

References & Citations

[1]Zhenkai WangA Fluorescent Probe with Zwitterionic ESIPT Feature for Ratiometric Monitoring of Peroxynitrite In Vitro and In Vivo. Anal Chem. 2024 Feb 27;96 (8) :3600-3608.

Shipping Conditions

Room temperature

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Frequently Asked Questions

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