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CPI-637

Product Specifications

CAS Number

1884712-47-3

Target

Epigenetic Reader Domain

Applications

Epigenetics

Smiles

CC1CC (=O) NC2=CC=CC (=C2N1) C3=CC4=C (C=C3) N (N=C4C5=CN (N=C5) C) C

Molecular Formula

C22H22N6O

Additionnal Information

CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor with IC50 values of 0.03 μM and 0.051μM for CBP and EP300 respectively in TR-FRET assay. It is highly selective against other bromodomains, displaying substantial biochemical activity only against BRD9.

Storage Conditions

2 years -80 in solvent

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