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Devimistat (CPI-613)

Product Specifications

CAS Number

95809-78-2

Target

Dehydrogenase

Applications

Metabolism

Smiles

C1=CC=C (C=C1) CSCCC (CCCCC (=O) O) SCC2=CC=CC=C2

Molecular Formula

C22H28O2S2

Additionnal Information

Devimistat (CPI-613), a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase in NCI-H460 cell line, disrupts tumor cell mitochondrial metabolism. CPI-613 induces apoptosis in pancreatic cancer cells. Phase 2.

Storage Conditions

2 years -80 in solvent

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