TPBM
Product Specifications
CAS Number
6466-43-9
Target
Estrogen Receptor/ERR, Others
Related Pathways
Others, Endocrinology/Hormones
Bioactivity
TPBM is a potent inhibitor of estrogen receptor α (ERα) . The IC 50 value of TPBM for 17β-estradiol (E2) -ERα is 9 μM. TPBM is not toxic to cells and reduces E2·ERα recruitment to an endogenous estrogen-responsive gene. TPBM inhibits E2-dependent growth of ERα-positive cancer cells with an IC 50 value of 5 μM. TPBM does not affect estrogen-independent cell growth [1].
Smiles
O=C1C2=C(N=C(CSCC3=CC=CC=C3)N2)N(C)C(=O)N1C
Molecular Formula
C15H16N4O2S
Molecular Weight
316.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
EH26842 96 Tests
Human GNaI3 (G Protein Alpha Inhibiting Activity Polypeptide 3) ELISA Kit
Sign In for Pricing
View Details 
MBS1491571-01 0.05 mg
Rabbit anti-Mouse C-X-C motif chemokine 9 polyclonal Antibody, HRP conjugated
Sign In for Pricing
View Details MBS1491571-02 0.1 mg
Rabbit anti-Mouse C-X-C motif chemokine 9 polyclonal Antibody, HRP conjugated
Sign In for Pricing
View Details MBS1491571-03 5x 0.1 mg
Rabbit anti-Mouse C-X-C motif chemokine 9 polyclonal Antibody, HRP conjugated
Sign In for Pricing
View Details 127430-ML750 100 µL
GNG5 (Guanine Nucleotide-binding Protein G (I) /G (S) /G (O) Subunit gamma-5, GNGT5, FLJ92393) (MaxLight 750) discontinued
Sign In for Pricing
View Details