Macrocarpal C

Macrocarpal C can be isolated from the 95 % ethanol extract of fresh leaves of E. globulus. Macrocarpal C inhibits the growth of T. mentagrophytes via an increase in the permeability of the fungal membrane. Macrocarpal C increases the production of intracellular ROS and induces apoptosis as a consequence of DNA fragmentation[1].

Product Specifications

CAS Number

[142628-53-3]

UNSPSC

12352005

Target

Fungal

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/macrocarpal-c.html

Purity

95.0

Solubility

10 mM in DMSO

Smiles

CC(C)C[C@@H](C1=C(C(C=O)=C(C(C=O)=C1O)O)O)[C@@]2([C@@]3([H])[C@@]4([H])[C@](CCC([C@]3([H])CC2)=C)([H])C4(C)C)C

Molecular Formula

C28H38O5

Molecular Weight

454.60

References & Citations

[1]Jack Ho Wong, et al. Antifungal mode of action of macrocarpal C extracted from Eucalyptus globulus Labill (Lan An) towards the dermatophyte Trichophyton mentagrophytes. Chin Med. 2015, 10, 34.