LYG-409
Product Specifications
CAS Number
3053857-55-6
SKU
C03615-5mg
Target
E3 Ligase
Applications
Ubiquitin
Additionnal Information
LYG-409 is a potent, selective, and orally bioavailable degrader of GSPT1, with a DC50 of 7.87 nM. It exhibits strong antiproliferative activity in KG-1 cells with an IC50 of 9.50 nM and demonstrates significant antitumor efficacy in vivo in models of acute myeloid leukemia and prostate cancer.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb2921096-01 20 µg
Recombinant Pelotomaculum thermopropionicum UPF0756 membrane protein PTH_1817 (PTH_1817)
Sign In for Pricing
View Details orb2921096-02 100 µg
Recombinant Pelotomaculum thermopropionicum UPF0756 membrane protein PTH_1817 (PTH_1817)
Sign In for Pricing
View Details