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GLP-1R modulator L7-028

GLP-1R modulator L7-028 is an allosteric modulator enhancing GLP-1 binding to GLP-1R via a transmembrane site (EC50 11.01 ± 2.73 μM) .

Product Specifications

CAS Number

2648317-95-5

UNSPSC

12352005

Target

GCGR

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/glp-1r-modulator-l7-028.html

Concentration

10mM

Purity

99.47

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=CC(OC2CCCC2)=C1)NC3=CC(C(N4CCCCC4)=O)=CC=C3

Molecular Formula

C24H28N2O3

Molecular Weight

392.49

References & Citations

[1]Wang J, et al. Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site. ACS Chem Biol. 2021 Nov 19;16 (11) :2444-2452.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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