BDNF Human, HEK

Source: HEK293 Cells.Filtered White lyophilized (freeze-dried) powder.BDNF promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. BDNF is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the cns. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (ltp), long-term depression (ltd), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.BDNF Human Recombinant is a single, glycosylated polypeptide chain containing 116 amino acids (19-128a.a) and having a molecular mass of 13.1kDa (calculated) . BDNF is fused to a 6 a.a His tag at C-terminal.

Product Specifications

Product Name Alternative

Brain-Derived Neurotrophic Factor, BDNF, MGC34632, Abrineurin, ANON2, BULN2.

Purification

Greater than 95.0% as determined by SDS-PAGE.

Components

BDNF filtered (0.4 μm) and lyophilized from 0.5mg/mL in PBS.It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/mL and let the lyophilized pellet dissolve completely.

Storage Conditions

Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.