Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

MRP1-IN-2

MRP1-IN-2 (Compound 21) is a selective MRP1 inhibitor with a relatively weak inhibitory effect on P-gp. MRP1-IN-2 exhibits a strong accumulation effect of calcein, with its EC50 value being 177 nM. MRP1-IN-2 enhances the activity of Doxorubicin on drug-resistant cells. MRP1-IN-2 can be used for the study of multidrug-resistant cancers[1].

Product Specifications

UNSPSC

12352005

Target

P-glycoprotein

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Cancer

Smiles

NC1=NC(N2CC3(CCOCC3)C2)=C(C(C)CC)C(C4=C(F)C(F)=CC=C4)=N1

Molecular Formula

C21H26F2N4O

Molecular Weight

388.45

References & Citations

[1]Čičak M, et al. The 2-aminopyrimidine ring as a new scaffold for potent MRP1 inhibitors. Eur J Med Chem. 2026 Jan 15;302 (Pt 3) :118364.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

ExoBriteTM 560/585 CD9 (Mouse) Flow Antibody (100 tests)
P018-560-500 1x 500 µL

ExoBriteTM 560/585 CD9 (Mouse) Flow Antibody (100 tests)

Sign In for Pricing
View Details
Recombinant MUC4 Monoclonal Antibody
AN301419L-01 50 µL

Recombinant MUC4 Monoclonal Antibody

Sign In for Pricing
View Details
Recombinant MUC4 Monoclonal Antibody
AN301419L-02 100 µL

Recombinant MUC4 Monoclonal Antibody

Sign In for Pricing
View Details
Frozen Tissue Blocks, Pleura
CB501802 1 Block

Frozen Tissue Blocks, Pleura

Sign In for Pricing
View Details
HMG1 (HMGB1) Mouse Monoclonal Antibody [Clone ID: KS1]
AM26447AF-N 100 µg

HMG1 (HMGB1) Mouse Monoclonal Antibody [Clone ID: KS1]

Sign In for Pricing
View Details
TRIM45 Rabbit Polyclonal Antibody
TA367316 100 µL

TRIM45 Rabbit Polyclonal Antibody

Sign In for Pricing
View Details