Recombinant MUC4 Monoclonal Antibody
Product Specifications
Background
May play a role in tumor progression. Ability to promote tumor growth may be mainly due to repression of apoptosis as opposed to proliferation. Has anti-adhesive properties. Seems to alter cellular behavior through both anti-adhesive effects on cell-cell and cell-extracellular matrix interactions and in its ability to act as an intramembrane ligand for ERBB2. Plays an important role in cell proliferation and differentiation of epithelial cells by inducing specific phosphorylation of ERBB2.
Abbreviation
MUC4
UniProt
Q99102
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human MUC4 fragment
Target
Mucin; MUC; MUC4; ASGP; HSA276359; MUC-4; mucin-4
Clonality
Monoclonal,Recombinant
Clone
A114
Conjugation
Unconjugated
Applications
IHC
Field of Research
Microbiology; Signal Transduction; Cancer
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
IHC 1:200-1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG, κ
Available Sizes
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