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Recombinant MUC4 Monoclonal Antibody

Product Specifications

Background

May play a role in tumor progression. Ability to promote tumor growth may be mainly due to repression of apoptosis as opposed to proliferation. Has anti-adhesive properties. Seems to alter cellular behavior through both anti-adhesive effects on cell-cell and cell-extracellular matrix interactions and in its ability to act as an intramembrane ligand for ERBB2. Plays an important role in cell proliferation and differentiation of epithelial cells by inducing specific phosphorylation of ERBB2.

Abbreviation

MUC4

UniProt

Q99102

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant human MUC4 fragment

Target

Mucin; MUC; MUC4; ASGP; HSA276359; MUC-4; mucin-4

Clonality

Monoclonal,Recombinant

Clone

A114

Conjugation

Unconjugated

Applications

IHC

Field of Research

Microbiology; Signal Transduction; Cancer

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

IHC 1:200-1:1000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product MSDS

https://789.bio/eb/gVKF3FGK

Isotype

IgG, κ

Available Sizes

Curated Selection

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