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QSY-21

QSY-21 is a fluorescence quencher. QSY-21 possesses broad absorption in far red and NIR range, and can quench fluorescence of dyes that emit in this region. This is a carboxylic acid derivative. QSY-21 has intense absorption maximum at 661 nm, making it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications. It is a common quencher for Cyanine5, Cyanine5.5, AF 647, or other spectrally similar fluorescent dyes.

Product Specifications

CAS Number

[1200894-41-2]

UNSPSC

12171500

Target

Fluorescent Dye

Related Pathways

Others

Field of Research

Others

Purity

98.77

Smiles

O=C(C1CCN(S(=O)(C2=C(C3=C4C=CC(N5C6=C(CC5)C=CC=C6)=CC4=[O+]C7=C3C=CC(N8C9=C(CC8)C=CC=C9)=C7)C=CC=C2)=O)CC1)O.[Cl-]

Molecular Formula

C41H36ClN3O5S

Molecular Weight

718.26

References & Citations

[1]Takahashi S, et al. Reversible off-on fluorescence probe for hypoxia and imaging of hypoxia-normoxia cycles in live cells. J Am Chem Soc. 2012 Dec 5;134 (48) :19588-91.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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