USP28-IN-4
USP28-IN-4 is a potent USP28 inhibitor with an IC50 value of 0.04 μM against USP28. USP28-IN-4 exhibits anticancer activity and inhibits USP2, USP7, USP8, USP9x, UCHL3 and UCHL5. USP28-IN-4 is cytotoxic to human colorectal and lung squamous carcinoma cells and dose-dependently downregulates c-Myc cellular levels through the ubiquitin-proteasome system. -proteasome system to dose-dependently downregulate cellular levels of c-Myc.
Product Specifications
CAS Number
2931509-15-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
461.36
Molecular Formula
C22H18Cl2N2O3S
Notes
Research use only, not for human use.
Receptor
DUB
Available Sizes
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