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USP28-IN-4

USP28-IN-4 is a potent USP28 inhibitor with an IC50 value of 0.04 μM against USP28. USP28-IN-4 exhibits anticancer activity and inhibits USP2, USP7, USP8, USP9x, UCHL3 and UCHL5. USP28-IN-4 is cytotoxic to human colorectal and lung squamous carcinoma cells and dose-dependently downregulates c-Myc cellular levels through the ubiquitin-proteasome system. -proteasome system to dose-dependently downregulate cellular levels of c-Myc.

Product Specifications

CAS Number

2931509-15-6

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

461.36

Molecular Formula

C22H18Cl2N2O3S

Notes

Research use only, not for human use.

Receptor

DUB

Available Sizes

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