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ALEPH (hydrochloride)

ALEPH (hydrochloride) is the h5-HT2A and h5-HT2B partial agonist with the EC50 values of 10.3 nM and 19.2 nM, respectively. ALEPH (hydrochloride) causes head twitch response in mice (ED50: 0.80 mg/kg) [1].

Product Specifications

CAS Number

61638-08-2

UNSPSC

12352005

Target

5-HT Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

COC(C=C1SC)=C(CC(C)N)C=C1OC.Cl

Molecular Formula

C12H20ClNO2S

Molecular Weight

277.81

References & Citations

[1]Halberstadt AL, et al. Use of the head-twitch response to investigate the structure-activity relationships of 4-thio-substituted 2,5-dimethoxyphenylalkylamines. Psychopharmacology (Berl) . 2023 Jan;240 (1) :115-126.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT2 Receptor; α-1 microglobulin

Available Sizes

Frequently Asked Questions

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