Smo antagonist M25
Smo antagonist M25 is a smoothened antagonist for inhibition of the hedgehog pathway.
Product Specifications
CAS Number
[1186293-14-0]
UNSPSC
12352005
Target
Hedgehog; Smo
Related Pathways
Stem Cell/Wnt
Field of Research
Cancer
Smiles
O=C(NCC1=CC=C2N(N=CC2=C1)C3=CC=CC=C3OC)C(CCC)CCC
Molecular Formula
C23H29N3O2
Molecular Weight
379.50
References & Citations
[1]Dessole G, Branca D, Ferrigno F, Kinzel O, Muraglia E, Palumbi MC, Rowley M, Serafini S, Steinkühler C, Jones P. Discovery of N-[ (1-aryl-1H-indazol-5-yl) methyl]amides derivatives as smoothened antagonists for inhibition of the hedgehog pathway. Bioorg Med Chem Lett. 2009 Aug 1;19 (15) :4191-5. doi: 10.1016/j.bmcl.2009.05.112. Epub 2009 Jun 2. PMID: 19540115.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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