RO27-3225
Product Specifications
CAS Number
274682-89-2
Target
Melanocortin Receptor
Related Pathways
GPCR/G Protein, Neuroscience
Bioactivity
RO27-3225 is a potent and selective agonist of the melanocortin 4 receptor (MC4R), with EC50 values of 1 nM for MC4R and 8 nM for MC1R. It demonstrates approximately 30-fold selectivity for MC4R over MC3R. RO27-3225 exhibits neuroprotective and anti-inflammatory properties.
Smiles
C([C@H](NC([C@@H](NC([C@@H](CC1=CC=CC=C1)NC([C@H](CC2=CN=CN2)NC(CCC)=O)=O)=O)CCCNC(=N)N)=O)C(N(CC(N)=O)C)=O)C=3C=4C(NC3)=CC=CC4
Molecular Formula
C39H52N12O6
Molecular Weight
784.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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