Antibacterial agent 159

Compound 6d (Antibacterial agent 159) is an antibiotic effective against impetigo and Clostridium difficile infection (CDI), with no observed recurrence for CDI and minimal impact on the beneficial gut microbiome [1].

O=[N+](C1=CN=C(C)N1CCNC(/C(NC(C2=CSC(C3=CSC(C4=CC=C(C5=NC(C(N[C@@](C(N/C(C6=NC(C(N[C@H](C7=NC(C(N8)=O)=CS7)C(C)C)=O)=CS6)=C\C)=O)([H])[C@H](O)C)=O)=CS5)C(C9=CSC([C@]8([H])[C@H](O)C)=N9)=N4)=N3)=N2)=O)=C/C)=O)[O-]