CIDD-8633
CIDD-8633 is a potent inhibitor of DDR2 with an IC50 of 6.105 μM. It significantly suppresses the proliferation of MIA-PaCa-2 and AsPC-1 cells, with IC25 values of 4.0 and 5.5 μM, respectively. Additionally, CIDD-8633 hinders cell migration, arrests the cell cycle, induces apoptosis (apoptosis), and substantially reduces the growth of pancreatic ductal adenocarcinoma (PDAC) tumors. This compound is applicable in pancreatic cancer research, including studies on PDAC.
Product Specifications
CAS Number
1428356-95-9
Field of Research
Cell Biology, Immunology & Inflammation, Protein Biochemistry, Signal Transduction
Smiles
O=C (NC1=CC=C (C=C1) NC2=NC (=NC (=C2) C) NCC) COC3=NN=C (C=C3) N4N=CC=C4
Molecular Formula
C22H23N9O2
Molecular Weight
445.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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