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CIDD-8633

CIDD-8633 is a potent inhibitor of DDR2 with an IC50 of 6.105 μM. It significantly suppresses the proliferation of MIA-PaCa-2 and AsPC-1 cells, with IC25 values of 4.0 and 5.5 μM, respectively. Additionally, CIDD-8633 hinders cell migration, arrests the cell cycle, induces apoptosis (apoptosis), and substantially reduces the growth of pancreatic ductal adenocarcinoma (PDAC) tumors. This compound is applicable in pancreatic cancer research, including studies on PDAC.

Product Specifications

CAS Number

1428356-95-9

Field of Research

Cell Biology, Immunology & Inflammation, Protein Biochemistry, Signal Transduction

Smiles

O=C (NC1=CC=C (C=C1) NC2=NC (=NC (=C2) C) NCC) COC3=NN=C (C=C3) N4N=CC=C4

Molecular Formula

C22H23N9O2

Molecular Weight

445.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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