KR30031
Product Specifications
CAS Number
205535-74-6
Target
Others|||P-gp
Related Pathways
Others|||Membrane transporter/Ion channel|||Neuroscience
Bioactivity
KR30031 is a novel P-glycoprotein inhibitor with potential anticancer activity. KR30031 is a verapamil analog with fewer cardiovascular effects. The ability of KR-30031 to reduce this efflux transport is equal to that of verapamil, a well-known P-glycoprotein inhibitor. The bioavailability of paclitaxel could be enhanced by coadministration of a P-glycoprotein inhibitor, KR-30031.
Smiles
C(CCN(CCC1=CC(OC)=C(OC)C=C1)C)C2(C#N)C=3C(CC2)=C(OC)C(OC)=CC3
Molecular Formula
C26H34N2O4
Molecular Weight
438.56
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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