RIPK1-IN-23
Product Specifications
CAS Number
3031534-16-1
Target
Necroptosis, RIP kinase
Related Pathways
Apoptosis, NF-κB
Bioactivity
RIPK1-IN-23 (compound 19) is an RIPK1 inhibitor with potent anti-necroptotic effects in HT-29 cells (EC50 = 1.7 nM) . Additionally, RIPK1-IN-23 exhibits anti-inflammatory properties.
Smiles
CN1C=2C(=CC=C(C2)C3=CC=C(C#N)C=C3)OC[C@H](NC(=O)C=4NC(CC5=CC=CC=C5)=NN4)C1=O
Molecular Formula
C27H22N6O3
Molecular Weight
478.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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