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Trans-VH032-Cyclopropane-F-C-cyclohexane-p-C-OTs

Product Specifications

Target

E3 Ligase Ligand-Linker Conjugate

Related Pathways

PROTAC

Bioactivity

Trans-VH032-Cyclopropane-F-C-cyclohexane-p-C-OTs contains a VHL ligand for recruiting E3 ubiquitin ligase and a PROTAC linker. VHL Ligand-Linker Conjugates 15 is applicable for the synthesis of PROTACs, such as dBAZ2B.

Smiles

CC1=CC=C(C=C1)S(=O)(=O)OCC2CCC(CC2)COC3=C(C=CC(=C3)C4=C(N=CS4)C)CNC(=O)[C@@H]5C[C@H](CN5C(=O)[C@H](C(C)(C)C)NC(=O)C6(CC6)F)O

Molecular Formula

C41H53FN4O8S2

Molecular Weight

813.01

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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