Proxyfan
Product Specifications
CAS Number
177708-09-7
Target
Histamine Receptor
Related Pathways
Neuroscience|||Immunology/Inflammation|||GPCR/G Protein
Purity
0.9968
Bioactivity
Proxyfan (Proxifan) is a high-affinity protean antagonist/agonist of histamine H3 receptors with a full spectrum of pharmacological activity ranging from full agonist to full inverse agonist (antagonist), depending on the competition between constitutively active and resting H3 receptors within a given tissue or brain region.Proxyfan acts as a neutral antagonist in the feeding-associated ventral medial nucleus of the hypothalamus, and as a agonist in the basolateral amygdala of the rat (BLA) .
Smiles
N1=CNC(=C1)CCCOCC=2C=CC=CC2
Molecular Formula
C13H16N2O
Molecular Weight
216.28
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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