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Proxyfan

Product Specifications

CAS Number

177708-09-7

Target

Histamine Receptor

Related Pathways

Neuroscience|||Immunology/Inflammation|||GPCR/G Protein

Purity

0.9968

Bioactivity

Proxyfan (Proxifan) is a high-affinity protean antagonist/agonist of histamine H3 receptors with a full spectrum of pharmacological activity ranging from full agonist to full inverse agonist (antagonist), depending on the competition between constitutively active and resting H3 receptors within a given tissue or brain region.Proxyfan acts as a neutral antagonist in the feeding-associated ventral medial nucleus of the hypothalamus, and as a agonist in the basolateral amygdala of the rat (BLA) .

Smiles

N1=CNC(=C1)CCCOCC=2C=CC=CC2

Molecular Formula

C13H16N2O

Molecular Weight

216.28

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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