ERK1/2 inhibitor 11
Product Specifications
Target
Apoptosis, Caspase, ERK
Related Pathways
Apoptosis, MAPK, Proteases/Proteasome
Bioactivity
ERK1/2 inhibitor 11 (compound L6) is a dual inhibitor of ERK1/2 that promotes the accumulation of DSBs and the degradation of ERK1/2 expression. This compound decreases BCL-2 levels and induces DNA damage by inhibiting PARP and ERK1/2. Additionally, ERK1/2 inhibitor 11 activates caspase 3 to induce apoptosis.
Smiles
OC1=CC(NC(/C2=N\NC(NN3CCCCCC3)=S)=O)=C2C=C1
Molecular Formula
C15H19N5O2S
Molecular Weight
333.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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