Recombinant human Ubiquitin/RPS27A protein

Ubiquitin is a small protein that is composed of 76 amino acids and its sequence is highly conserved throughout evolution from invertebrates to mammals. In the cytoplasm, ubiquitin is involved in ATP-dependent nonlysomal proteolysis of various proteins. In the nucleus, ubiquitin is conjugated to histone2A and may play a role in regulation of chromatin structure and/or regulation of transcriptional activity. ubiquitin (76amino acid) was overexpressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Ribosomal protein S27a, Ubiquitin carboxyl extension protein 80, Small ribosomal subunit protein eS31, UBA80, UBCEP1, UBCEP80

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by BCA assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

8.6 kDa (76aa) confirmed by MALDI-TOF

Additionnal Information

Ubiquitin, RPS27A, uBA80, uBCEP1, uBA52, uBCEP2, uBB, uBC, ubiquitin, FLJ25987, MGC8385, Polyubiquitin B, ubiquitin B, UBC3002-10 µg, UBC3002-20 µg, UBC3002-50 µg, UBC3002-100 µg, UBC3002-250 µg, UBC3002-500 µg, UBC3002-1 mg, UBC3002-10, UBC3002-20, UBC3002-50, UBC3002-100, UBC3002-250, UBC3002-500, UBC3002-1

References & Citations

Lund PK., et al. (1985) J Biol. Chem. 260 (12), 7609-7613.; ; Pancre V., et al. (1991) Eur J Immunol. 21 (11) :2735-41.

Other References

Jeong WJ, et al. Ras stabilization through aberrant activation of Wnt/β-catenin signaling promotes intestinal tumorigenesis. (Sci Signal. 2012) {https://pubmed.ncbi.nlm.nih.gov/22494971/}