A-438079 HCl
Product Specifications
Background
A-438079 (899431-18-6) is a competitive P2X7 receptor antagonist (pIC50 = 6.9) .1 Displayed antinociceptive effects in a rat model of neuropathic pain.2 A-438079 prevented the LPS-induced release of IL-1ß and attenuated LPS-induced (via intrathecal lumbar injection) mechanical hyperalgesia in rat hindpaws.3 It prevented mechanical hyperalgesia following peripheral nerve injury.4 A-438079 protected against cerebral ischemia/reperfusion injury in a rat model via reduction of the neuroinflammatory response.5
Conjugation
Unconjugated
Buffer
White or off-white solid
Storage Conditions
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
M04796-2-APC 100 µg/Vial
Anti-Annexin A3 Antibody Picoband® (monoclonal, 2H3H8), APC Conjugate
Sign In for Pricing
View Details 
