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Euphorbia Factor L2

Euphorbia factor L2, a lathyrane diterpenoid isolated from caper euphorbia seed (the seeds of Euphorbia lathyris L.), has been traditionally applied to treat cancer. Euphorbia factor L2 shows potent cytotoxicity and induces apoptosis via a mitochondrial pathway[1].

Product Specifications

CAS Number

[218916-51-9]

UNSPSC

12352005

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/euphorbia-factor-l2.html

Concentration

10mM

Purity

99.90

Solubility

DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(/C(C)=C/[C@](C1(C)C)([H])[C@]1([H])C[C@H]2OC(C3=CC=CC=C3)=O)[C@](C[C@H](C)[C@@H]4OC(C5=CC=CC=C5)=O)(OC(C)=O)[C@@]4([H])[C@@H](OC(C)=O)C2=C

Molecular Formula

C38H42O9

Molecular Weight

642.73

References & Citations

[1]Lin M, et al. Euphorbia factor L2 induces apoptosis in A549 cells through the mitochondrial pathway. Acta Pharm Sin B. 2017 Jan;7 (1) :59-64.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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