Vinculin Monoclonal Antibody

Product Specifications

Background

Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament (F-actin) -binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It may also play important roles in cell morphology and locomotion. Vinculin is a 117-kDa,1,066-amino-acid protein which is ubiquitously expressed. Its splice variant, metavinculin (124 kDa), is muscle-specific.

Abbreviation

Vinculin

UniProt

P18206

Host

Mouse

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant human Vinculin protein expressed by E.coli

Target

Vinculin; Metavinculin (MV) ; VCL

Clonality

Monoclonal

Clone

4D4

Conjugation

Unconjugated

Applications

WB; IHC; IF

Field of Research

Cardiovascular; Signal Transduction; Isotype/Loading Controls; Epigenetics and Nuclear Signaling

Purification

Protein A/G Purification

Concentration

1 mg/mL

Dilution

WB 1:2000-1:4000; IHC 1:200-1:400; IF 1:200-1:400

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH 7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Protected from prolonged exposure to light.

Calculated Molecular Weight

124 kDa

Observed Molecular Weight

126 kDa

Isotype

IgG1

Available Sizes

Documents

Product Datasheet

Click to open

More Discoveries

Explore Other Products

Browse additional items from our catalog

2312-MSM1-P0 20ug

Anti-Filaggrin Antibody Clone FLG/1561, Unconjugated-20ug

View Details

LS008826-100ug 100 µg

IQGAP1 (NM_003870) Human Over-expression Lysate

View Details

SI208209B 1 Each

Rat Mcf2 Pre-designed siRNA Set B

View Details

RD-DNAH11-Hu-48Tests 48 Tests

Human Dynein, Axonemal, Heavy Chain 11 (DNAH11) ELISA Kit

View Details

NB100-77903DL594 0.1 mL

Mouse Monoclonal CD24 Antibody (ML5) [DyLight 594]

View Details

MF-0157864-01 5 mg

Aurein 5.2

View Details