Recombinant CHIKV Spike glycoprotein E1 Protein, C-Fc

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus responsible for Chikungunya fever, a disease marked by fever, rash, and joint pain. The E1 envelope glycoprotein, a 47 kDa class II fusion protein, plays a critical role in viral entry by mediating low pH-triggered membrane fusion within host endosomes. It forms heterodimers with E2 glycoproteins, assembling into spike trimers on the viral surface that facilitate host cell attachment and infection. Due to its essential function in viral infectivity, the E1 protein is widely used in studies of viral entry, antibody development, vaccine design, and diagnostic assay optimization.

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Recombinant CHIKV Spike glycoprotein E1 Protein is produced by our Mammalian expression system and the target gene encoding Tyr810-Lys1221 is expressed with a hFc-tag at the C-terminus.