ABBV-CLS-7262
ABBV-CLS-7262 is modulates the integrated stress response (ISR) for inhibition of ISR-related diseases[1].
Product Specifications
CAS Number
[2945073-88-9]
Product Name Alternative
Fosigotifator (THAM sodium)
UNSPSC
12352005
Target
Eukaryotic Initiation Factor (eIF)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/abbv-cls-7262.html
Purity
98.03
Smiles
O=C(COC(C=C1)=CC(F)=C1Cl)NC(CCC23NC(COC(C=C4)=CC(F)=C4Cl)=O)(CC2)[C@H](C3)OCO[P](O)(O[Na])=O.OCC(CO)(N)CO
Molecular Formula
C29H37Cl2F2N3NaO12P
Molecular Weight
782.48
References & Citations
[1]Martin, et al. Preparation of bicyclooctanyl diamide prodrugs as modulators of the integrated stress pathway useful in treatment of ISR-mediated disorders. World Intellectual Property Organization, WO2020077217 A1. 2020-04-16.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Curated Selection
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