ABBV-CLS-7262

ABBV-CLS-7262 is modulates the integrated stress response (ISR) for inhibition of ISR-related diseases[1].

Product Specifications

CAS Number

[2945073-88-9]

Product Name Alternative

Fosigotifator (THAM sodium)

UNSPSC

12352005

Target

Eukaryotic Initiation Factor (eIF)

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/abbv-cls-7262.html

Purity

98.03

Smiles

O=C(COC(C=C1)=CC(F)=C1Cl)NC(CCC23NC(COC(C=C4)=CC(F)=C4Cl)=O)(CC2)[C@H](C3)OCO[P](O)(O[Na])=O.OCC(CO)(N)CO

Molecular Formula

C29H37Cl2F2N3NaO12P

Molecular Weight

782.48

References & Citations

[1]Martin, et al. Preparation of bicyclooctanyl diamide prodrugs as modulators of the integrated stress pathway useful in treatment of ISR-mediated disorders. World Intellectual Property Organization, WO2020077217 A1. 2020-04-16.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

Phase 3

Available Sizes

Curated Selection

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