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Tip5 Rabbit Polyclonal Antibody

Product Specifications

Background

Function:May play a role in transcriptional regulation interacting with ISWI. May serve a specific role in maintaining or altering the chromatin structure of the rDNA locus., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., sequence caution:Contaminating sequence. Potential poly-A sequence., similarity:Belongs to the WAL family., similarity:Contains 1 bromo domain., similarity:Contains 1 DDT domain., similarity:Contains 1 MBD (methyl-CpG-binding) domain., similarity:Contains 1 PHD-type zinc finger., similarity:Contains 4 A.T hook DNA-binding domains., subcellular location:Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus., subunit:Together with SMARCA5, it forms a complex termed NoRC (nucleolar remodeling complex) ., tissue specificity:Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney and pancreas., function:May play a role in transcriptional regulation interacting with ISWI. May serve a specific role in maintaining or altering the chromatin structure of the rDNA locus., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., sequence caution:Contaminating sequence. Potential poly-A sequence., similarity:Belongs to the WAL family., similarity:Contains 1 bromo domain., similarity:Contains 1 DDT domain., similarity:Contains 1 MBD (methyl-CpG-binding) domain., similarity:Contains 1 PHD-type zinc finger., similarity:Contains 4 A.T hook DNA-binding domains., subcellular location:Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus., subunit:Together with SMARCA5, it forms a complex termed NoRC (nucleolar remodeling complex) ., tissue specificity:Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney and pancreas.

Product Name Alternative

BAZ2A; KIAA0314; TIP5; Bromodomain adjacent to zinc finger domain protein 2A; Transcription termination factor I-interacting protein 5; TTF-I-interacting protein 5; Tip5; hWALp3

Gene Name

BAZ2A

Gene ID

605682

Swiss Prot

Q9UIF9

Host

Rabbit

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, IHC

Purification

Affinity purification

Dilution

WB 1:500-1:2000, IHC 1:50-1:300

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Molecular Weight

210kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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