BEPP (hydrochloride)
BEPP hydrochloride is a double-stranded RNA-dependent protein kinase (PKR) inducer and antiviral agent. BEPP hydrochloride effectively inhibits the growth of human lung cancer cell lines overexpressing PKR and induces apoptosis and activates caspase-3 in sensitive cells. In addition, BEPP hydrochloride can also significantly inhibit vaccinia virus replication[1].
Product Specifications
CAS Number
[455311-98-5]
UNSPSC
12352005
Target
Apoptosis; Caspase
Related Pathways
Apoptosis
Field of Research
Cancer; Infection
Purity
96.94
Solubility
DMSO : 4.17 mg/mL (ultrasonic)
Smiles
OC(COC1=CC=CC=C1)CN2C3=CC=CC=C3N(CC4=CC=CC=C4)C2=N.Cl
Molecular Formula
C23H24ClN3O2
Molecular Weight
409.91
References & Citations
[1]Hu W, et al. Double-stranded RNA-dependent protein kinase-dependent apoptosis induction by a novel small compound. J Pharmacol Exp Ther. 2009 Mar;328 (3) :866-72.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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