BEPP (hydrochloride)

BEPP hydrochloride is a double-stranded RNA-dependent protein kinase (PKR) inducer and antiviral agent. BEPP hydrochloride effectively inhibits the growth of human lung cancer cell lines overexpressing PKR and induces apoptosis and activates caspase-3 in sensitive cells. In addition, BEPP hydrochloride can also significantly inhibit vaccinia virus replication[1].

Product Specifications

CAS Number

[455311-98-5]

UNSPSC

12352005

Target

Apoptosis; Caspase

Related Pathways

Apoptosis

Field of Research

Cancer; Infection

Purity

96.94

Solubility

DMSO : 4.17 mg/mL (ultrasonic)

Smiles

OC(COC1=CC=CC=C1)CN2C3=CC=CC=C3N(CC4=CC=CC=C4)C2=N.Cl

Molecular Formula

C23H24ClN3O2

Molecular Weight

409.91

References & Citations

[1]Hu W, et al. Double-stranded RNA-dependent protein kinase-dependent apoptosis induction by a novel small compound. J Pharmacol Exp Ther. 2009 Mar;328 (3) :866-72.