Tyrosine Hydroxylase (phospho Ser31) Antibody

Product Specifications

Background

Plays an important role in the physiology of adrenergic neurons.

NCBI Gene ID

7054

Swiss Prot

P07101

Accession Number

NP_000351.2

Host

Rabbit

Reactivity

Human, Rat

Immunogen

Tyrosine Hydroxylase (Phospho-Ser31) antibody was raised against a peptide sequence around phosphorylation site of serine31 (V-T-S (p) -P-R) derived from human Tyrosine Hydroxylase.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific, Neuroscience

Purification

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

55 - 60 kDa

Specificity

This antibody detects endogenous levels of Tyrosine Hydroxylase only when phosphorylated at serine 31.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

NCBI Official Name

Tyrosine hydroxylase

NCBI Organism

Homo sapiens

Background Reference 01

Vazin T, et al. Stem Cells. 2008 Jun;26 (6) : 1517-25Pistocchi A, et al. BMC Dev Biol. 2008 Mar 10;8:27 Fukakusa A, et al. J Pharmacol Sci. 2008 Feb;106 (2) : 321-4.