ICOS Antibody

Product Specifications

Background

ICOS belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.

NCBI Gene ID

29851

Swiss Prot

Q9Y6W8

Accession Number

Q9Y6W8

Host

Rabbit

Reactivity

Human

Immunogen

This ICOS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the C-terminal region of human ICOS.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

23 kDa

Fragment

Rabbit Ig

Symbol

ICOS

NCBI Official Name

Inducible T-cell costimulator

NCBI Organism

Homo sapiens

Background Reference 01

Okamoto, N., et al., Biochem. Biophys. Res. Commun. 310 (3) :691-702 (2003) .

Background Reference 02

Okamoto, T., et al., J. Rheumatol. 30 (6) :1157-1163 (2003) .

Background Reference 03

Riley, J.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (18) :11790-11795 (2002) .

Background Reference 04

Haimila, K.E., et al., Immunogenetics 53 (12) :1028-1032 (2002) .

Other Product Names

Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule, CD278, ICOS, AILIM

Tested Applications

WB, IHC-P, Flow

Protein ID

50400701

Physical Properties

Liquid

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