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RNF111 Antibody

Product Specifications

Background

The protein encoded by this gene contains a RING finger domain, a motif known to be involved in protein-protein and protein-DNA interactions. The mouse counterpart of this gene (Rnf111/arkadia) has been shown to genetically interact with the transforming growth factor (TGF) beta-like factor Nodal, and act as a modulator of the nodal signaling cascade, which is essential for the induction of mesoderm during embryonic development. [provided by RefSeq].

NCBI Gene ID

54778

Swiss Prot

Q6ZNA4

Accession Number

Q6ZNA4

Host

Rabbit

Reactivity

Human

Immunogen

This RNF111 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-237 amino acids from the N-terminal region of human RNF111.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=59-964

Calculated Molecular Weight

109 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RNF111

NCBI Official Name

E3 ubiquitin-protein ligase Arkadia

NCBI Organism

Homo sapiens

Background Reference 01

Nagano, Y., et al. J. Biochem. 147 (4) :545-554 (2010)

Background Reference 02

Cunnington, R.H., et al. Can. J. Physiol. Pharmacol. 87 (10) :764-772 (2009)

Background Reference 03

Markson, G., et al. Genome Res. 19 (10) :1905-1911 (2009)

Background Reference 04

Van Wijk, S.J., et al. Mol. Syst. Biol. 5, 295 (2009) :

Other Product Names

E3 ubiquitin-protein ligase Arkadia, 632-, RING finger protein 111, RNF111

Tested Applications

WB

Protein ID

308153555

Physical Properties

Liquid

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