21-Desacetyldeflazacort
21-Desacetyldeflazacort (21-desDFZ) is the active metabolite of Deflazacort (HY-13609) . Deflazacort is an anti-inflammatory and immunosuppressant. Deflazacort is an inactive pro-drug which can be rapidly converted by esterases to the active metabolite 21-desacetyldeflazacort after oral administration[1].
Product Specifications
CAS Number
[13649-57-5]
Product Name Alternative
21-desDFZ
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/21-desacetyldeflazacort.html
Purity
99.23
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(CC4)=CC(C=C5)=O)C)([H])[C@H](C3)O)([H])C[C@@]1([H])OC(C)=N2)C)=O
Molecular Formula
C23H29NO5
Molecular Weight
399.48
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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