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TBCA Antibody

Product Specifications

Background

The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. This gene encodes chaperonin cofactor A.

NCBI Gene ID

6902

Swiss Prot

O75347

Accession Number

O75347

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This TBCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-58 amino acids from the Central region of human TBCA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=56-183

Calculated Molecular Weight

13 kDa

Fragment

Rabbit Ig

Symbol

TBCA

NCBI Official Name

Tubulin-specific chaperone A

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34 (5) :800-812 (2010)

Background Reference 03

Bruneel, A., et al. Proteomics 5 (15) :3876-3884 (2005)

Background Reference 04

Nolasco, S., et al. FEBS Lett. 579 (17) :3515-3524 (2005)

Other Product Names

Tubulin-specific chaperone A, TCP1-chaperonin cofactor A, Tubulin-folding cofactor A, CFA, TBCA

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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