GCHFR Antibody
Product Specifications
Background
GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.
NCBI Gene ID
2644
Swiss Prot
P30047
Accession Number
NP_005249
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GCHFR.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10409 - Fetal Liver Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GCHFR antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=25-878
Calculated Molecular Weight
10 kDa
Applications Notes
GCHFR antibody can be used for detection of GCHFR by ELISA at 1:312500. GCHFR antibody can be used for detection of GCHFR by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
GCHFR
NCBI Official Name
GTP cyclohydrolase I feedback regulator
NCBI Organism
Homo sapiens
Background Reference 01
Ohta, E., (2006) Arch. Neurol. 63 (11), 1605-1610.
Other Product Names
GCHFR, GFRP, HsT16933, MGC138467, MGC138469, P35
Tested Applications
ELISA, WB
Protein ID
4885257
Physical Properties
Liquid
Curated Selection
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