S-Adenosylhomocysteine sulfoxide
S-Adenosylhomocysteine sulfoxide is an inhibitor of catechol-O-methyltransferase (COMT) with an IC50 value of 860 μM. S-Adenosylhomocysteine sulfoxide can be used in the research of methylation reaction modulators[1].
Product Specifications
CAS Number
[29907-86-6]
UNSPSC
12352005
Target
COMT
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/s-adenosylhomocysteine-sulfoxide.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CS(CC[C@@H](C(O)=O)N)=O)O3
Molecular Formula
C14H20N6O6S
Molecular Weight
400.41
References & Citations
[1]Coward J K, et al. Inhibition of catechol-O-methyltransferase by S-adenosylhomocysteine and S-adenosylhomocysteine sulfoxide, a potential transition-state analog[J]. Biochemical pharmacology, 1972, 21 (8) : 1200-1203.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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