PPARGC1B Antibody

Product Specifications

Background

The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

133522

Swiss Prot

Q86YN6

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 850-950 of human PPARGC1B (NP_001166170.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 113kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

PPARGC1B

Positive Control 2

MCF7

Positive Control 3

Mouse brain

NCBI Official Name

PPARG coactivator 1 beta

NCBI Organism

Homo sapiens

Other Product Names

ERRL1, PERC, PGC-1 (beta), PGC1B, peroxisome proliferator-activated receptor gamma coactivator 1-beta, PGC-1-related estrogen receptor alpha coactivator, PPAR-gamma coactivator 1-beta, PPARGC-1-beta, PPARgamma coactivator 1 beta, peroxisome proliferator-activated receptor gamma, coactivator 1 beta