JAKMIP2 Antibody

Product Specifications

Background

JAKMIP2 Antibody: JAKMIP2, also known as neuroendocrine long coiled-coil protein 1 (NECC1), is a member of the JAKMIP family of proteins whose members are thought play a role in JAK1 signaling and the regulation of microtubule cytoskeleton rearrangements. JAKMIP2 is expressed predominantly in neuronal cells but unlike JAKMIP1, JAKMIP2 localizes to the Golgi complex. It has been suggested that JAKMIP2 may play important roles in the control of the regulated secretory pathway.

NCBI Gene ID

9832

Swiss Prot

Q96AA8

Accession Number

NP_055605

Host

Rabbit

Reactivity

Human, Mouse

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

JAKMIP2 Antibody is affinity chromatography purified via peptide column.

Positive Control

Cat. No. 1403 - Mouse Brain Tissue Lysate

Concentration

1 mg/mL

Buffer

JAKMIP2 Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

JAKMIP2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Calculated Molecular Weight

Predicted: 89 kDa

Fragment

IgG

Specificity

At least four isoforms of JAKMIP2 are known to exist; this antibody will detect all four isoforms. JAKMIP2 antibody is predicted to not cross-react with JAKMIP1.

Symbol

JAKMIP2

NCBI Official Name

Janus kinase and microtubule interacting protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Steindler C, Li Z, Algarte M, et al. Jamip1 (Marlin-1) defines a family of proteins interacting with Janus kinases and microtubules. J. Biol. Chem. 2004; 279:43168-77.

Background Reference 02

Cruz-Garcia D, Vazquez-Martinez R, Peinado JR, et al. Identification and characterization of two novel (neuro) endocrine long coiled-coil proteins. FEBS Lett. 2007; 581:3149-56.