Misp (NM_030218) Mouse Recombinant Protein
Product Specifications
Background
Plays a role in mitotic spindle orientation and mitotic progression. Regulates the distribution of dynactin at the cell cortex in a PLK1-dependent manner, thus stabilizing cortical and astral microtubule attachments required for proper mitotic spindle positioning. May link microtubules to the actin cytoskeleton and focal adhesions. May be required for directed cell migration and centrosome orientation. May also be necessary for proper stacking of the Golgi apparatus (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse mitotic spindle positioning (Misp), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
9130017N09Rik
Gene ID
78906
UniProt
Q9D279
Accession Number mRNA
NM_030218
Chromosomal Location
10 C1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
72.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Misp
Species
Mouse
Protein ID
NP_084494
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/78906
Uniprot URL
https://www.uniprot.org/uniprot/Q9D279
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_030218
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_084494
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