CD8B Antibody - middle region: FITC (ARP42715_P050-FITC)
Product Specifications
Gene Name
CD8b molecule
Gene Aliases
LY3, P37, LEU2, LYT3, CD8B1
Gene ID
926
Swiss Prot
P10966
Accession Number
NP_757362
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human CD8B
Target
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8B is the CD8 beta chain isoforms.
Partner Proteins
ELAVL1; CD8A; CD3D; CD8B; ST3GAL4; LCK
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
25kDa
Shipping Conditions
Wet Ice
Protein Length
243
NCBI Gene Symbol
CD8B
Protein Name
T-cell surface glycoprotein CD8 beta chain
Nucleotide Accession Number
NM_172213
Curated Selection
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