CPI-1612
Product Specifications
CAS Number
2374971-81-8
Target
Epigenetic Reader Domain
Applications
Epigenetics
Molecular Formula
C27H26N6O
Additionnal Information
CPI-1612 is a highly potent, orally active inhibitor of EP300/CBP histone acetyltransferase (HAT) . It displays an IC50 of 8.0 nM for EP300 HAT. CPI-1612 suppresses H3K27 acetylation in vivo and exhibits efficacy in JEKO-1 mantle cell lymphoma xenograft at a low dose. CPI-1612 displays anticancer activity.
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