VEGF Receptor 2 (KDR) Mouse Monoclonal Antibody [Clone ID: LBI12C1]

Product Specifications

Background

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]

Overview

KDR mouse monoclonal antibody, clone LBI12C1

Synonyms

CD309; FLK1; VEGFR; VEGFR2

Gene Name

Kinase insert domain receptor

Gene ID

3791

UniProt

P35968

Conjugation

Unconjugated

Related Pathways

Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, VEGF signaling pathway

Field of Research

Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, VEGF signaling pathway

Concentration

1 mg/ml

Dilution

WB 1:2000

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.