Promegestone
Product Specifications
UNSPSC Description
Promegestone (R-5020), a progestin, is a potent progesterone receptor (PR) agonist. Promegestone has the potential for endocrine regulation and cancer research[1].
Target Antigen
Progesterone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Cancer; Endocrinology
Assay Protocol
https://www.medchemexpress.com/promegestone.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@](C)(CC[C@]1([C@@]3(CCC4=CC(CCC4=C3CC2)=O)[H])[H])C(CC)=O
Molecular Weight
326.47
References & Citations
[1]Clémentine Garoche, et al. Human and Zebrafish Nuclear Progesterone Receptors Are Differently Activated by Manifold Progestins. Environ Sci Technol. 2020 Aug 4;54(15):9510-9518.|[2]Michael A Kirby, et al. Progesterone Receptor-Mediated Actions Regulate Remodeling of the Cervix in Preparation for Preterm Parturition. Reprod Sci. 2016 Nov;23(11):1473-1483.|[3]Todd P Knutson, et al. Posttranslationally modified progesterone receptors direct ligand-specific expression of breast cancer stem cell-associated gene programs. J Hematol Oncol. 2017 Apr 17;10(1):89.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-119384/Promegestone-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-119384/Promegestone-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
34184-77-5
Available Sizes
Curated Selection
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